Target：PTN9

Gene Name：PTPN9

Protein Name：Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase MEG2)

Human Gene Id：5780

Human Swiss Prot No：P43378

Mouse Swiss Prot No：O35239

Rat Swiss Prot No：Q641Z2

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：PTN9 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：65kD

Background： The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis. [provided by RefSeq, Jul 2008],

Function：catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:Protein-tyrosine phosphatase that could participate in the transfer of hydrophobic ligands or in functions of the Golgi apparatus.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class 3 subfamily.,similarity:Contains 1 CRAL-TRIO domain.,similarity:Contains 1 tyrosine-protein phosphatase domain.,

Subcellular Location：Cytoplasm .

Expression： Brain,Pancreas,Placenta,