Target：PKAγ cat
Fields：Endocrine resistance;MAPK signaling pathway;Ras signaling pathway;Calcium signaling pathway;cAMP signaling pathway;Chemokine signaling pathway;Oocyte meiosis;Autophagy - animal;Longevity regulating pathway;Longevity regulating pathway - multiple species;Adrenergic signaling in cardiomyocytes;Vascular smooth muscle contraction;Wnt signaling pathway;Hedgehog signaling pathway;Apelin signaling pathway;Tight junction;Gap junction;Platelet activation;Circadian entrainment;Thermogenesis;Long-term potentiation;Retrograde endocannabinoid signaling;Glutamatergic synapse;Cholinergic synapse;Serotonergic synapse;GABAergic synapse;Dopaminergic synapse;Olfactory transduction;Taste transduction;Inflammatory mediator regulation of TRP channels;Insulin signaling pathway;Insulin secretion;GnRH signaling pathway;Ovarian steroidogenesis;Progesterone-mediated oocyte maturation;Estrogen signaling pathway;Melanogenesis;Thyroid hormo
Gene Name：PRKACG
Protein Name：cAMP-dependent protein kinase catalytic subunit gamma
Human Gene Id：5568
Human Swiss Prot No：P22612
Immunogen：The antiserum was produced against synthesized peptide derived from human KAPCG. AA range:1-50
Specificity：PKAγ cat Polyclonal Antibody detects endogenous levels of PKAγ cat protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：PRKACG;cAMP-dependent protein kinase catalytic subunit gamma;PKA C-gamma
Observed Band(KD)：40kD
Background： Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit. [provided by RefSeq, Jul 2008],
Function：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activated by cAMP.,function:Phosphorylates a large number of substrates in the cytoplasm and the nucleus.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,subunit:A number of inactive tetrameric holoenzymes are produced by the combination of homo- or heterodimers of the different regulatory subunits associated with two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits.,tissue specificity:Testis specific. But important tissues such as brain and ovary have not been analyzed for the content of transcript.,
Subcellular Location：nucleoplasm,cytosol,ciliary base,
Expression：Testis specific. But important tissues such as brain and ovary have not been analyzed for the content of transcript.
