Target:RACK7
Gene Name:ZMYND8
Protein Name:Protein kinase C-binding protein 1
Human Gene Id:23613
Human Swiss Prot No:Q9ULU4
Immunogen:The antiserum was produced against synthesized peptide derived from human PKCB1. AA range:581-630
Specificity:RACK7 Polyclonal Antibody detects endogenous levels of RACK7 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:ZMYND8;KIAA1125;PRKCBP1;RACK7;Protein kinase C-binding protein 1;Cutaneous T-cell lymphoma-associated antigen se14-3;CTCL-associated antigen se14-3;Rack7;Zinc finger MYND domain-containing protein 8
Observed Band(KD):132kD
Background: The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Function:PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 bromo domain.,similarity:Contains 1 MYND-type zinc finger.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 PWWP domain.,subunit:Interacts in vitro with PRKCB1.,tissue specificity:Expressed in all tissues examined with highest expression in brain, lung, pancreas, and placenta. Expressed in cutaneous T-cell lymphomas (CTCL).,
Subcellular Location:Nucleus . Cytoplasm . Sequestered in the cytoplasm through the interaction with DBN1. .
Expression:Expressed in all tissues examined with highest expression in brain, lung, pancreas, and placenta. Expressed in cutaneous T-cell lymphomas (CTCL).