Target：RB33B

Fields：Autophagy - animal

Gene Name：RAB33B

Protein Name：Ras-related protein Rab-33B

Human Gene Id：83452

Human Swiss Prot No：Q9H082

Mouse Swiss Prot No：O35963

Immunogen：Synthesized peptide derived from human protein . at AA range: 100-180

Specificity：RB33B Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：25kD

Background： This gene encodes a small GTP-binding protein of the Rab GTPase family, whose members function in vesicle transport during protein secretion and endocytosis. Rab GTPases are active, membrane-associated proteins that recruit effector proteins in the GTP-bound state and inactive cytosolic proteins when in a GDP-bound state. The protein encoded by this gene is ubiquitously expressed and has been implicated in Golgi to endoplasmic reticulum cycling of Golgi enzymes. In addition, this protein regulates Golgi homeostasis and coordinates intra-Golgi retrograde trafficking. Allelic variants in this gene have been associated with Dyggve-Melchior-Clausen syndrome and Smith-McCort dysplasia 2, which are autosomal recessive spondyloepimetaphyseal dysplasias characterized by skeletal abnormalities. [provided by RefSeq, Sep 2016],

Function：function:Protein transport. Probably involved in vesicular traffic.,similarity:Belongs to the small GTPase superfamily. Rab family.,

Subcellular Location：Golgi apparatus membrane ; Lipid-anchor . Golgi apparatus, cis-Golgi network . Under starvation conditions punctate RAB33B-positive structures are often observed in the cytoplasm. .

Expression： Brain,Testis,Tongue,