Target：Rap 2C

Fields：Tight junction

Gene Name：RAP2C

Protein Name：Ras-related protein Rap-2c

Human Gene Id：57826

Human Swiss Prot No：Q9Y3L5

Mouse Gene Id：72065

Mouse Swiss Prot No：Q8BU31

Immunogen：The antiserum was produced against synthesized peptide derived from human RAP2C. AA range:97-146

Specificity：Rap 2C Polyclonal Antibody detects endogenous levels of Rap 2C protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：RAP2C;Ras-related protein Rap-2c

Observed Band(KD)：26kD

Background： The protein encoded by this gene is a member of the Ras-related protein subfamily of the Ras GTPase superfamily. Members of this family are small GTPases that act as molecular switches to regulate cellular proliferation, differentiation, and apoptosis. This protein has been reported to activate in vitro transcriptional activity of the serum response element. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012],

Function：similarity:Belongs to the small GTPase superfamily. Ras family.,tissue specificity:Expressed in mononuclear leukocytes and megakaryocytes. Not detected in platelets.,

Subcellular Location：Cytoplasm . Recycling endosome membrane ; Lipid-anchor ; Cytoplasmic side .

Expression：Expressed in liver, skeletal muscle, prostate, uterus, rectum, stomach, and bladder and to a lower extent in brain, kidney, pancreas, and bone marrow. Expressed in mononuclear leukocytes and megakaryocytes.