Target：RGMA

Fields：TGF-beta signaling pathway;Axon guidance

Gene Name：RGMA RGM

Protein Name：Repulsive guidance molecule A (RGM domain family member A)

Human Gene Id：56963

Human Swiss Prot No：Q96B86

Mouse Swiss Prot No：Q6PCX7

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：RGMA Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：49kD

Background： This gene encodes a member of the repulsive guidance molecule family. The encoded protein is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. This protein may also function as a tumor suppressor in some cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],

Function：function:Repulsive guidance molecules (Rgm) are involved in the guidance of growth cones of the developing neurons.,similarity:Belongs to the repulsive guidance molecule (RGM) family.,

Subcellular Location：Cell membrane ; Lipid-anchor, GPI-anchor .

Expression： Retina,Teratocarcinoma,Testis,Uterus,