Target:RFX2
Gene Name:RFX2
Protein Name:DNA-binding protein RFX2
Human Gene Id:5990
Human Swiss Prot No:P48378
Mouse Swiss Prot No:P48379
Immunogen:The antiserum was produced against synthesized peptide derived from human RFX2. AA range:661-710
Specificity:RFX2 Polyclonal Antibody detects endogenous levels of RFX2 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:RFX2;DNA-binding protein RFX2;Regulatory factor X 2
Molecular Weight(Da):80kD
Background: This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008],
Function:similarity:Belongs to the RFX family.,
Subcellular Location:Nucleus . Cytoplasm . Mainly expressed in the nucleus and at lower level in cytoplasm. .