Target：RANG

Fields：Human T-cell leukemia virus 1 infection;Viral carcinogenesis

Gene Name：RANBP1

Protein Name：Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1)

Human Gene Id：5902

Human Swiss Prot No：P43487

Mouse Swiss Prot No：P34022

Immunogen：Synthesized peptide derived from human protein . at AA range: 30-110

Specificity：RANG Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：22kD

Background： This gene encodes a protein that forms a complex with Ras-related nuclear protein (Ran) and metabolizes guanoside triphosphate (GTP). This complex participates in the regulation of the cell cycle by controlling transport of proteins and nucleic acids into the nucleus. There are multiple pseudogenes for this gene on chromosomes 9, 12, 17, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Function：function:Inhibits GTP exchange on Ran. Forms a Ran-GTP-RANBP1 trimeric complex. Increase GTP hydrolysis induced by the Ran GTPase activating protein RANGAP1. May act in an intracellular signaling pathway which may control the progression through the cell cycle by regulating the transport of protein and nucleic acids across the nuclear membrane.,similarity:Belongs to the RANBP1 family.,similarity:Contains 1 RanBD1 domain.,

Subcellular Location：intracellular,nucleus,nuclear envelope,cytoplasm,centrosome,cell-cell adherens junction,axon cytoplasm,

Expression： Blood,