Target：Rag C

Fields：Autophagy - animal;mTOR signaling pathway;Shigellosis

Gene Name：RRAGC

Protein Name：Ras-related GTP-binding protein C

Human Gene Id：64121

Human Swiss Prot No：Q9HB90

Mouse Gene Id：54170

Mouse Swiss Prot No：Q99K70

Immunogen：The antiserum was produced against synthesized peptide derived from human RRAGC. AA range:302-351

Specificity：Rag C Polyclonal Antibody detects endogenous levels of Rag C protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300; IP 1:50-200 ELISA 2000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：RRAGC;Ras-related GTP-binding protein C;Rag C;RagC;GTPase-interacting protein 2;TIB929

Observed Band(KD)：44kD

Background： This gene encodes a member of the GTR/RAG GTP-binding protein family. The encoded protein is a monomeric guanine nucleotide-binding protein which forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. The encoded protein promotes intracellular localization of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012],

Function：function:Has guanine nucleotide-binding activity but weak intrinsic GTPase activity.,similarity:Belongs to the GTR/RAG GTP-binding protein family.,subcellular location:Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA.,subunit:Forms a heterodimer with RRAGA in a sequence-independent manner. Binds GTP. Interacts with NOL8 and RRAGB.,

Subcellular Location：Cytoplasm . Nucleus . Lysosome . Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA (PubMed:11073942). .

Expression： Lymph,Ovary,