Target：TALK-2

Gene Name：KCNK17

Protein Name：Potassium channel subfamily K member 17

Human Gene Id：89822

Human Swiss Prot No：Q96T54

Immunogen：The antiserum was produced against synthesized peptide derived from human KCNK17. AA range:271-320

Specificity：TALK-2 Polyclonal Antibody detects endogenous levels of TALK-2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：KCNK17;TALK2;TASK4;Potassium channel subfamily K member 17;2P domain potassium channel Talk-2;Acid-sensitive potassium channel protein TASK-4;TWIK-related acid-sensitive K(+) channel 4;TWIK-related alkaline pH-activated K(+) channel

Observed Band(KD)：37-42kD

Background：potassium two pore domain channel subfamily K member 17(KCNK17) Homo sapiens The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is activated at alkaline pH. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008],

Function：function:Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents.,miscellaneous:Inhibited by Ba(2+), quinidine, chloroform and halothane. Activated at alkaline pH. Activated by quinine and isoflurane.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Homodimer .,

Subcellular Location：Membrane; Multi-pass membrane protein.

Expression： Adrenal gland,Lung,Pancreas,Spleen,