Target：RBAK

Fields：Herpes simplex virus 1 infection

Gene Name：RBAK

Protein Name：RB-associated KRAB zinc finger protein

Human Gene Id：57786

Human Swiss Prot No：Q9NYW8

Mouse Gene Id：57782

Mouse Swiss Prot No：Q8BQC8

Immunogen：The antiserum was produced against synthesized peptide derived from human RBAK. AA range:1-50

Specificity：RBAK Polyclonal Antibody detects endogenous levels of RBAK protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000; IF ICC 1:50-200;ELISA 1:2000-20000;IHC 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：RBAK;ZNF769;RB-associated KRAB zinc finger protein;RB-associated KRAB repressor;hRBaK;Zinc finger protein 769

Observed Band(KD)：85kD

Background： This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011],

Function：function:May repress E2F-dependent transcription. May promote AR-dependent transcription.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 16 C2H2-type zinc fingers.,subunit:Interacts with AR and RB1. May also interact with other nuclear hormone receptors such as NR3C1/GR.,tissue specificity:Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta.,

Subcellular Location：Nucleus .

Expression：Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta.