Target：TEFF1
Gene Name：TMEFF1 C9orf2
Protein Name：Tomoregulin-1 (TR-1) (H7365) (Transmembrane protein with EGF-like and one follistatin-like domain)
Human Gene Id：100526694
Human Swiss Prot No：Q8IYR6
Mouse Swiss Prot No：Q6PFE7
Rat Swiss Prot No：Q9QYV1
Immunogen：Synthesized peptide derived from part region of human protein
Specificity：TEFF1 Polyclonal Antibody detects endogenous levels of protein.
Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500-2000 ELISA 1:5000-20000
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD)：41kD
Background：function:May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.,similarity:Belongs to the tomoregulin family.,similarity:Belongs to the UPF0439 family.,similarity:Contains 1 EGF-like domain.,similarity:Contains 2 Kazal-like domains.,subunit:May interact with ST14.,tissue specificity:Expressed in brain.,tissue specificity:Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues.,
Function：function:May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.,similarity:Belongs to the tomoregulin family.,similarity:Belongs to the UPF0439 family.,similarity:Contains 1 EGF-like domain.,similarity:Contains 2 Kazal-like domains.,subunit:May interact with ST14.,tissue specificity:Expressed in brain.,tissue specificity:Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues.,
Subcellular Location：Cell membrane ; Single-pass type I membrane protein .
Expression：Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues.
