Target：TCP-1 θ

Gene Name：CCT8

Protein Name：T-complex protein 1 subunit theta

Human Gene Id：10694

Human Swiss Prot No：P50990

Mouse Gene Id：12469

Mouse Swiss Prot No：P42932

Immunogen：The antiserum was produced against synthesized peptide derived from human CCT8. AA range:361-410

Specificity：TCP-1 θ Polyclonal Antibody detects endogenous levels of TCP-1 θ protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CCT8;C21orf112;CCTQ;KIAA0002;T-complex protein 1 subunit theta;TCP-1-theta;CCT-theta;Renal carcinoma antigen NY-REN-15

Observed Band(KD)：60kD

Background： This gene encodes the theta subunit of the CCT chaperonin, which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of newly synthesized proteins. Alternative splicing results in multiple transcript variants of this gene. A pseudogene related to this gene is located on chromosome 1. [provided by RefSeq, Sep 2013],

Function：function:Molecular chaperone; assist the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.,similarity:Belongs to the TCP-1 chaperonin family.,subunit:Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. Interacts with PACRG.,

Subcellular Location：Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, cilium basal body .

Expression： Adipose tissue,B-cell lymphoma,Bone marrow,Chondrosarcoma,Epitheliu