Target:TCF25
Gene Name:TCF25 KIAA1049 NULP1 FKSG26
Protein Name:Transcription factor 25 (TCF-25) (Nuclear localized protein 1)
Human Gene Id:22980
Human Swiss Prot No:Q9BQ70
Mouse Swiss Prot No:Q8R3L2
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:TCF25 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):74kD
Background: TCF25 is a member of the basic helix-loop-helix (bHLH) family of transcription factors that are important in embryonic development (Steen and Lindholm, 2008 [PubMed 18068114]).[supplied by OMIM, Sep 2008],
Function:domain:The C-terminal region mediates transcriptional repression.,function:May play a role in cell death control. Acts as a transcriptional repressor. Has been shown to repress transcription of SRF in vitro and so may play a role in heart development.,similarity:Belongs to the TCF25 family.,subcellular location:Some staining in the cytosol.,subunit:Interacts with XIAP.,tissue specificity:In the embryo, widely expressed with highest levels in brain. In the adult, highest expression is found in the heart.,
Subcellular Location:Nucleus . Some staining in the cytosol.
Expression:In the embryo, widely expressed with highest levels in brain. In the adult, highest expression is found in the heart.