Target：TBX2

Gene Name：TBX2

Protein Name：T-box transcription factor TBX2

Human Gene Id：6909

Human Swiss Prot No：Q13207

Mouse Gene Id：21385

Mouse Swiss Prot No：Q60707

Immunogen：The antiserum was produced against synthesized peptide derived from human TBX2. AA range:251-300

Specificity：TBX2 Polyclonal Antibody detects endogenous levels of TBX2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：TBX2;T-box transcription factor TBX2;T-box protein 2

Observed Band(KD)：74kD

Background： This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. [provided by RefSeq, Jul 2008],

Function：function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation.,similarity:Contains 1 T-box DNA-binding domain.,tissue specificity:Expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary.,

Subcellular Location：Nucleus .

Expression：Expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary.