Target:FPRL2
Fields:Neuroactive ligand-receptor interaction;Neutrophil extracellular trap formation;Staphylococcus aureus infection
Gene Name:FPR3
Protein Name:N-formyl peptide receptor 3
Human Gene Id:2359
Human Swiss Prot No:P25089
Immunogen:The antiserum was produced against synthesized peptide derived from human FPRL2. AA range:304-353
Specificity:FPRL2 Polyclonal Antibody detects endogenous levels of FPRL2 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:FPR3;FPRH1;FPRL2;N-formyl peptide receptor 3;FMLP-related receptor II;FMLP-R-II;Formyl peptide receptor-like 2
Molecular Weight(Da):40kD
Background:function:Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Function:function:Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Subcellular Location:Cell membrane; Multi-pass membrane protein.
Expression:Detected in various tissues with highest expression in lung.