Target:TH
Gene Name:TH
Protein Name:Tyrosine 3-monooxygenase
Human Swiss Prot No:P07101
Rat Gene Id:25085
Rat Swiss Prot No:P04177
Immunogen:The antiserum was produced against synthesized peptide derived from human Tyrosine Hydroxylase. AA range:5-54
Specificity:TH Polyclonal Antibody detects endogenous levels of TH protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000.IHC:1:50-300 ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:TH;TYH;Tyrosine 3-monooxygenase;Tyrosine 3-hydroxylase;TH
Observed Band(KD):58kD
Background:Tyrosine 3-monooxygenase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have be associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.