Target:TFIIIC110
Gene Name:GTF3C2
Protein Name:General transcription factor 3C polypeptide 2
Human Gene Id:2976
Human Swiss Prot No:Q8WUA4
Mouse Swiss Prot No:Q8BL74
Immunogen:The antiserum was produced against synthesized peptide derived from human TF3C2. AA range:71-120
Specificity:TFIIIC110 Polyclonal Antibody detects endogenous levels of TFIIIC110 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:GTF3C2;KIAA0011;General transcription factor 3C polypeptide 2;TF3C-beta;Transcription factor IIIC 110 kDa subunit;TFIIIC 110 kDa subunit;TFIIIC110;Transcription factor IIIC subunit beta
Observed Band(KD):100kD
Background:function:Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1.,similarity:Contains 4 WD repeats.,subunit:Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6.,
Function:function:Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1.,similarity:Contains 4 WD repeats.,subunit:Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6.,
Subcellular Location:Nucleus.
Expression: Bone marrow,Brain,Colon,Epithelium,