Target：Tetraspanin-8

Gene Name：TSPAN8

Protein Name：Tetraspanin-8

Human Gene Id：7103

Human Swiss Prot No：P19075

Mouse Swiss Prot No：Q8R3G9

Immunogen：The antiserum was produced against synthesized peptide derived from human TSPAN8. AA range:96-145

Specificity：Tetraspanin-8 Polyclonal Antibody detects endogenous levels of Tetraspanin-8 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：TSPAN8;TM4SF3;Tetraspanin-8;Tspan-8;Transmembrane 4 superfamily member 3;Tumor-associated antigen CO-029

Observed Band(KD)：26kD

Background： The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008],

Function：similarity:Belongs to the tetraspanin (TM4SF) family.,tissue specificity:Gastric, colon, rectal, and pancreatic carcinomas.,

Subcellular Location：Membrane; Multi-pass membrane protein.

Expression：Gastric, colon, rectal, and pancreatic carcinomas.