Target：UB2Q1

Fields：Ubiquitin mediated proteolysis

Gene Name：UBE2Q1 NICE5 UBE2Q PRO3094

Protein Name：Ubiquitin-conjugating enzyme E2 Q1 (EC 6.3.2.19) (Protein NICE-5) (Ubiquitin carrier protein Q1) (Ubiquitin-protein ligase Q1)

Human Gene Id：55585

Human Swiss Prot No：Q7Z7E8

Mouse Swiss Prot No：Q7TSS2

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：UB2Q1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：46kD

Background： The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is 98% identical to the mouse counterpart. [provided by RefSeq, Jul 2008],

Function：catalytic activity:ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.,function:Catalyzes the covalent attachment of ubiquitin to other proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the ubiquitin-conjugating enzyme family.,tissue specificity:Widely expressed.,

Subcellular Location：Nucleus . Cell projection, filopodium . Cytoplasm, cytosol .

Expression：Widely expressed.