Target：TMPO

Gene Name：TMPO LAP2

Protein Name：thymopoietin

Human Gene Id：7112

Human Swiss Prot No：P42166/P42167

Immunogen：Synthetic peptide from human protein at AA range: 1-50

Specificity：The antibody detects endogenous TMPO protein

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：TMPO LAP2

Observed Band(KD)：75kD,50kD

Background：The protein encoded by TMPO (thymopoietin) resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in TMPO are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for TMPO.

Function：regulation of transcription,

Subcellular Location：Nucleus. Chromosome. Expressed diffusely throughout the nucleus.

Expression：Expressed in many tissues. Most abundant in adult thymus and fetal liver.