Target：TMEM185A

Gene Name：TMEM185A

Protein Name：Transmembrane protein 185A

Human Gene Id：84548

Human Swiss Prot No：Q8NFB2

Immunogen：The antiserum was produced against synthesized peptide derived from human TMEM185A. AA range:290-339

Specificity：TMEM185A Polyclonal Antibody detects endogenous levels of TMEM185A protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：TMEM185A;CXorf13;FAM11A;Transmembrane protein 185A;Protein FAM11A

Observed Band(KD)：41kD

Background： The protein encoded by this gene is predicted to be a transmembrane protein. This gene is best known for localizing to the CpG island of the fragile site FRAXF. The 5' untranslated region of this gene contains a CGG trinucleotide repeat sequence that normally consists of 7-40 tandem CGG repeats but which can expand to greater than 300 repeats. Methylation of the CpG island leads to transcriptional silencing of this gene, but neither the silencing nor an expanded repeat region appear to manifest itself in a clear phenotypic manner. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Aug 2013],

Function：similarity:Belongs to the TMEM185 family.,

Subcellular Location：Cell projection, dendrite . Membrane ; Multi-pass membrane protein .

Expression： Brain,Iris,Liver,PCR rescued clones,Testis,