Target:TMED1
Gene Name:TMED1 IL1RL1L IL1RL1LG
Protein Name:Transmembrane emp24 domain-containing protein 1 (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor-binding protein) (p24 family protein gamma-1) (Tp24) (p24gamma1)
Human Gene Id:11018
Human Swiss Prot No:Q13445
Mouse Swiss Prot No:Q3V009
Rat Swiss Prot No:Q5BK85
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:TMED1 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):24kD
Background: This gene belongs to the TMED (transmembrane emp24 domain-containing) protein family, which is involved in the vesicular trafficking of proteins. The protein encoded by this gene was identified by its interaction with interleukin 1 receptor-like 1 (IL1RL1) and may play a role in innate immunity. This protein lacks any similarity to other interleukin 1 ligands. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],
Function:function:Potential role in protein trafficking.,similarity:Belongs to the EMP24/GP25L family.,similarity:Contains 1 GOLD domain.,subunit:May interact with IL1RL1.,tissue specificity:Widely expressed.,
Subcellular Location:Cell membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Golgi apparatus, cis-Golgi network membrane ; Single-pass type I membrane protein . Endoplasmic reticulum-Golgi intermediate compartment membrane ; Single-pass type I membrane protein .
Expression:Widely expressed.