Target:TXND2
Gene Name:TXNDC2 SPTRX SPTRX1
Protein Name:Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1)
Human Gene Id:84203
Human Swiss Prot No:Q86VQ3
Mouse Swiss Prot No:Q6P902
Rat Swiss Prot No:Q5XHX6
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:TXND2 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):60kD
Background:function:Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.,similarity:Contains 1 thioredoxin domain.,subcellular location:In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece.,tissue specificity:Testis-specific. Only expressed during spermiogenesis, prominently in round and elongating spermatids.,
Function:function:Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.,similarity:Contains 1 thioredoxin domain.,subcellular location:In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece.,tissue specificity:Testis-specific. Only expressed during spermiogenesis, prominently in round and elongating spermatids.,
Subcellular Location:Cytoplasm . In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece.
Expression:Testis-specific. Only expressed during spermiogenesis, prominently in round and elongating spermatids.