Target：TRAK1

Gene Name：TRAK1 KIAA1042 OIP106

Protein Name：Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein)

Human Gene Id：22906

Human Swiss Prot No：Q9UPV9

Mouse Swiss Prot No：Q6PD31

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：TRAK1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：104kD

Background：PTM:O-glycosylated.,similarity:Contains 1 HAP1 N-terminal domain.,subunit:Interacts with O-GlcNAc transferase. Interacts with RHOT1/Miro-1 and RHOT2/Miro-2.,tissue specificity:High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined.,

Function：PTM:O-glycosylated.,similarity:Contains 1 HAP1 N-terminal domain.,subunit:Interacts with O-GlcNAc transferase. Interacts with RHOT1/Miro-1 and RHOT2/Miro-2.,tissue specificity:High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined.,

Subcellular Location：Cytoplasm . Nucleus . Mitochondrion . Early endosome . Endosome . Mitochondrion membrane . Cytoplasm, cell cortex . Predominantly associated with early endosome. The localization to early endosomes depends on its interaction with HGS/HRS (PubMed:18675823). Colocalizes with MGARP at the mitochondria (PubMed:19528298). .

Expression：High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined.