Target：Tra-2α

Fields：Spliceosome;Alcoholic liver disease

Gene Name：TRA2A

Protein Name：Transformer-2 protein homolog alpha

Human Gene Id：29896

Human Swiss Prot No：Q13595

Mouse Swiss Prot No：Q6PFR5

Immunogen：The antiserum was produced against synthesized peptide derived from human TRA-2 alpha. AA range:221-270

Specificity：Tra-2α Polyclonal Antibody detects endogenous levels of Tra-2α protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：TRA2A;Transformer-2 protein homolog alpha;TRA-2 alpha;TRA2-alpha;Transformer-2 protein homolog A

Observed Band(KD)：33kD

Background： This gene is a member of the transformer 2 homolog family and encodes a protein with several RRM (RNA recognition motif) domains. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013],

Function：function:Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing.,PTM:Phosphorylated in the RS domains.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Binds to A3 enhancer proteins SRp75, SRp55, SRp40 and SRp30.,

Subcellular Location：Nucleus .

Expression： Cervix carcinoma,Epithelium,Hepatocyte,Lung,Testis,Uterus,