Target：TPTE2

Gene Name：TPTE2 TPIP

Protein Name：Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (Lipid phosphatase TPIP) (TPTE and PTEN homologous inositol lipid phosphatase)

Human Gene Id：93492

Human Swiss Prot No：Q6XPS3

Immunogen：Synthesized peptide derived from human protein . at AA range: 300-380

Specificity：TPTE2 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：57kD

Background： TPIP is a member of a large class of membrane-associated phosphatases with substrate specificity for the 3-position phosphate of inositol phospholipids.[supplied by OMIM, Jul 2002],

Function：catalytic activity:Phosphatidylinositol 3,4,5-trisphosphate + H(2)O = phosphatidylinositol 4,5-bisphosphate + phosphate.,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,similarity:Contains 1 C2 tensin-type domain.,similarity:Contains 1 phosphatase tensin-type domain.,tissue specificity:Isoform 3 is expressed in testis, brain and stomach while isoform 4 seems to be testis-specific.,

Subcellular Location：[Isoform 3]: Endoplasmic reticulum membrane ; Multi-pass membrane protein .; [Isoform 1]: Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein .; [Isoform 4]: Cytoplasm .

Expression：Isoform 3 is expressed in testis, brain and stomach while isoform 4 seems to be testis-specific.