Target：TNNI3K
Gene Name：TNNI3K
Protein Name：Serine/threonine-protein kinase TNNI3K
Human Gene Id：51086
Human Swiss Prot No：Q59H18
Mouse Gene Id：435766
Mouse Swiss Prot No：Q5GIG6
Rat Gene Id：295531
Rat Swiss Prot No：Q7TQP6
Immunogen：The antiserum was produced against synthesized peptide derived from human TNNI3K. AA range:301-350
Specificity：TNNI3K Polyclonal Antibody detects endogenous levels of TNNI3K protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:10000. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：TNNI3K;CARK;Serine/threonine-protein kinase TNNI3K;Cardiac ankyrin repeat kinase;Cardiac troponin I-interacting kinase;TNNI3-interacting kinase
Molecular Weight(Da)：104kD
Background： This gene encodes a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases. The protein contains ankyrin repeat, protein kinase and serine-rich domains and is thought to play a role in cardiac physiology. [provided by RefSeq, Sep 2012],
Function：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,catalytic activity:GTP + beta-L-fucose 1-phosphate = diphosphate + GDP-L-fucose.,cofactor:Magnesium.,function:Catalyzes the formation of GDP-L-fucose from GTP and L-fucose-1-phosphate. Functions as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids.,function:May play a role in cardiac physiology.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 10 ANK repeats.,subcellular location:Expressed at lower levels in the cytoplasm.,subunit:Interacts with TNNI3, ACTC, ACTA1, MYBPC3, AIP, BABP3 and HADHB.,tissue specificity:Expressed in many tissues.,tissue specificity:Highly expressed in both adult and fetal heart.,
Subcellular Location：Nucleus . Cytoplasm . Expressed at lower levels in the cytoplasm.
Expression：Highly expressed in both adult and fetal heart.
