Target：TNFα-IP 2

Gene Name：TNFAIP2

Protein Name：Tumor necrosis factor alpha-induced protein 2

Human Gene Id：7127

Human Swiss Prot No：Q03169

Mouse Gene Id：21928

Mouse Swiss Prot No：Q61333

Immunogen：The antiserum was produced against synthesized peptide derived from human TNAP2. AA range:131-180

Specificity：TNFα-IP 2 Polyclonal Antibody detects endogenous levels of TNFα-IP 2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：TNFAIP2;Tumor necrosis factor alpha-induced protein 2;TNF alpha-induced protein 2;Primary response gene B94 protein

Molecular Weight(Da)：73kD

Background： This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that this gene may be a retinoic acid target gene in acute promyelocytic leukemia. [provided by RefSeq, Jul 2008],

Function：developmental stage:Differentially expressed in development and capillary tube-like formation in vitro.,function:May play a role as a mediator of inflammation and angiogenesis.,induction:By TNF-alpha and other proinflammatory factors.,similarity:Belongs to the SEC6 family.,

Subcellular Location：exocyst,extracellular space,

Expression： Umbilical vein endothelial cell,