Target：TNF-IP 1

Gene Name：TNFAIP1

Protein Name：BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

Human Gene Id：7126

Human Swiss Prot No：Q13829

Mouse Gene Id：21927

Mouse Swiss Prot No：O70479

Rat Gene Id：287543

Rat Swiss Prot No：Q7TNY1

Immunogen：The antiserum was produced against synthesized peptide derived from human TNAP1. AA range:71-120

Specificity：TNF-IP 1 Polyclonal Antibody detects endogenous levels of TNF-IP 1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：TNFAIP1;BACURD2;EDP1;BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2;hBACURD2;BTB/POZ domain-containing protein TNFAIP1;Protein B12;Tumor necrosis factor; alpha-induced protein 1, endothelial

Observed Band(KD)：34kD

Background： This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner. [provided by RefSeq, Jul 2008],

Function：function:Enhances the PCNA-dependent DNA polymerase delta activity.,induction:By TNF-alpha, interleukin-1 beta and lipopolysaccharide (LPS).,similarity:Belongs to the KCTD10/KCTD13/TNFAIP1 family.,similarity:Contains 1 BTB (POZ) domain.,subunit:Interacts with PCNA.,

Subcellular Location：Cytoplasm. Nucleus. Endosome. Colocalizes with RHOB in endosomes.

Expression： Amygdala,Endothelial cell,Epithelium,Lung,