Target:VAT1
Gene Name:VAT1
Protein Name:Synaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-)
Human Gene Id:10493
Human Swiss Prot No:Q99536
Mouse Swiss Prot No:Q62465
Rat Swiss Prot No:Q3MIE4
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:VAT1 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):43kD
Background:vesicle amine transport 1(VAT1) Homo sapiens Synaptic vesicles are responsible for regulating the storage and release of neurotransmitters in the nerve terminal. The protein encoded by this gene is an abundant integral membrane protein of cholinergic synaptic vesicles and is thought to be involved in vesicular transport. It belongs to the quinone oxidoreductase subfamily of zinc-containing alcohol dehydrogenase proteins. [provided by RefSeq, Jul 2008],
Function:similarity:Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.,
Subcellular Location:Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein. The majority is localized in the cytoplasm and a small amount is associated with mitochondria. .
Expression:Expressed in brain. Also expressed in glioblastoma cells.