Target:USP40
Gene Name:USP40
Protein Name:Ubiquitin carboxyl-terminal hydrolase 40
Human Gene Id:55230
Human Swiss Prot No:Q9NVE5
Mouse Swiss Prot No:Q8BWR4
Immunogen:The antiserum was produced against synthesized peptide derived from human USP40. AA range:1011-1060
Specificity:USP40 Polyclonal Antibody detects endogenous levels of USP40 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:USP40;Ubiquitin carboxyl-terminal hydrolase 40;Deubiquitinating enzyme 40;Ubiquitin thioesterase 40;Ubiquitin-specific-processing protease 40
Observed Band(KD):140kD
Background: Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP40 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008],
Function:catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:May be catalytically inactive.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Broadly expressed.,
Subcellular Location:nucleus,cytoplasm,
Expression:Broadly expressed.