Target:USP24
Gene Name:USP24
Protein Name:Ubiquitin carboxyl-terminal hydrolase 24
Human Gene Id:23358
Human Swiss Prot No:Q9UPU5
Mouse Gene Id:329908
Mouse Swiss Prot No:B1AY13
Immunogen:The antiserum was produced against synthesized peptide derived from human USP24. AA range:21-70
Specificity:USP24 Polyclonal Antibody detects endogenous levels of USP24 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:USP24;KIAA1057;Ubiquitin carboxyl-terminal hydrolase 24;Deubiquitinating enzyme 24;Ubiquitin thioesterase 24;Ubiquitin-specific-processing protease 24
Molecular Weight(Da):211kD
Background: Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008],
Function:catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 UBA domain.,
Subcellular Location:cytoplasm,
Expression: Brain,Epithelium,Placenta,Platelet,T-cell,