Target:UBE2Z
Fields:Ubiquitin mediated proteolysis
Gene Name:UBE2Z HOYS7
Protein Name:Ubiquitin-conjugating enzyme E2 Z (EC 6.3.2.19) (Uba6-specific E2 conjugating enzyme 1) (Use1) (Ubiquitin carrier protein Z) (Ubiquitin-protein ligase Z)
Human Gene Id:65264
Human Swiss Prot No:Q9H832
Mouse Swiss Prot No:Q3UE37
Rat Swiss Prot No:Q3B7D1
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:UBE2Z Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):38kD
Background: This gene encodes an enzyme which ubiquitinates proteins which participate in signaling pathways and apoptosis. [provided by RefSeq, Feb 2012],
Function:catalytic activity:ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.,function:Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Specific substrate for UBE1L2, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the ubiquitin-conjugating enzyme family.,tissue specificity:Widely expressed. Highly in placenta, pancreas, spleen and testis.,
Subcellular Location:Cytoplasm . Nucleus .
Expression:Widely expressed. Highly in placenta, pancreas, spleen and testis.