Target：UBCE7IP4
Gene Name：RNF144A
Protein Name：Probable E3 ubiquitin-protein ligase RNF144A
Human Gene Id：9781
Human Swiss Prot No：P50876
Mouse Gene Id：108089
Mouse Swiss Prot No：Q925F3
Immunogen：The antiserum was produced against synthesized peptide derived from human RNF144A. AA range:151-200
Specificity：UBCE7IP4 Polyclonal Antibody detects endogenous levels of UBCE7IP4 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：RNF144A;KIAA0161;RNF144;UBCE7IP4;Probable E3 ubiquitin-protein ligase RNF144A;RING finger protein 144A;UbcM4-interacting protein 4;Ubiquitin-conjugating enzyme 7-interacting protein 4
Observed Band(KD)：30kD
Background： The protein encoded by this protein contains a RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. The mouse counterpart of this protein has been shown to interact with Ube2l3/UbcM4, which is an ubiquitin-conjugating enzyme involved in embryonic development. [provided by RefSeq, Jul 2008],
Function：caution:Lacks the His residue in the RING-type domain 2 that is one of the conserved features of the family.,function:E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the RBR family. RNF144 subfamily.,similarity:Contains 1 IBR-type zinc finger.,similarity:Contains 2 RING-type zinc fingers.,subunit:Interacts with UBE2L3.,
Subcellular Location：Cell membrane ; Single-pass membrane protein . Cytoplasmic vesicle membrane .
Expression： Bone marrow,Ovary,
