Target：VPREB

Gene Name：VPREB1 VPREB

Protein Name：Immunoglobulin iota chain (CD179 antigen-like family member A) (Protein VPreB1) (V(pre)B protein) (VpreB protein) (CD antigen CD179a)

Human Gene Id：7441

Human Swiss Prot No：P12018

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：VPREB Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：15kD

Background： The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],

Function：function:Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates ig gene rearrangements in the early steps of B-cell differentiation.,similarity:Belongs to the immunoglobulin superfamily.,subunit:Associates non-covalently with IGLL1.,tissue specificity:Only expressed by pre-B-cells.,

Subcellular Location：Endoplasmic reticulum .

Expression：Only expressed by pre-B-cells.