Target:YYAP1
Gene Name:YY1AP1 HCCA2 YY1AP
Protein Name:YY1-associated protein 1 (Hepatocellular carcinoma susceptibility protein) (Hepatocellular carcinoma-associated protein 2)
Human Gene Id:55249
Human Swiss Prot No:Q9H869
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:YYAP1 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):87kD
Background: The encoded gene product presumably interacts with YY1 protein; however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Function:function:Enhances transcription activation by YY1.,sequence caution:Translated as Tyr.,similarity:Contains 1 Myb-like domain.,similarity:Contains 2 PAH (paired amphipathic helix) repeats.,subunit:Interacts with YY1.,tissue specificity:Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas.,
Subcellular Location:Cytoplasm . Nucleus . Nucleus, nucleoplasm . Nucleus, nucleolus .
Expression:Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas.