Target：ZNHIT1
Gene Name：ZNHIT1
Protein Name：Zinc finger HIT domain-containing protein 1
Human Gene Id：10467
Human Swiss Prot No：O43257
Mouse Gene Id：70103
Mouse Swiss Prot No：Q8R331
Immunogen：Synthesized peptide derived from ZNHIT1 . at AA range: 40-120
Specificity：ZNHIT1 Polyclonal Antibody detects endogenous levels of ZNHIT1 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：ZNHIT1;CGBP1;ZNFN4A1;Zinc finger HIT domain-containing protein 1;Cyclin-G1-binding protein 1;Zinc finger protein subfamily 4A member 1;p18 Hamlet
Observed Band(KD)：18-22kD
Background：function:Seems to play a role in p53-mediated apoptosis induction.,induction:Induced by DNA damage.,PTM:Phosphorylated on Thr by MAPK11 or MAPK14.,PTM:Stres-induced ZNHIT1 is mainly regulated at the level of protein.,similarity:Belongs to the ZNHIT1 family.,similarity:Contains 1 HIT-type zinc finger.,subunit:Interacts with MAPK11 and MAPK14. Component of the chromatin-remodeling SRCAP complex composed of at least SRCAP, DMAP1, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1.,
Function：function:Seems to play a role in p53-mediated apoptosis induction.,induction:Induced by DNA damage.,PTM:Phosphorylated on Thr by MAPK11 or MAPK14.,PTM:Stres-induced ZNHIT1 is mainly regulated at the level of protein.,similarity:Belongs to the ZNHIT1 family.,similarity:Contains 1 HIT-type zinc finger.,subunit:Interacts with MAPK11 and MAPK14. Component of the chromatin-remodeling SRCAP complex composed of at least SRCAP, DMAP1, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1.,
Subcellular Location：Nucleus .
Expression：Expressed abundantly in liver, but weakly in skeletal muscle, ovary and small intestine.
