Target：ZNF460

Fields：Herpes simplex virus 1 infection

Gene Name：ZNF460

Protein Name：Zinc finger protein 460

Human Gene Id：10794

Human Swiss Prot No：Q14592

Immunogen：The antiserum was produced against synthesized peptide derived from human ZNF460. AA range:461-510

Specificity：ZNF460 Polyclonal Antibody detects endogenous levels of ZNF460 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ZNF460;ZNF272;Zinc finger protein 460;Zinc finger protein 272;Zinc finger protein HZF8

Observed Band(KD)：64kD

Background：zinc finger protein 460(ZNF460) Homo sapiens Zinc finger proteins, such as ZNF272, interact with nucleic acids and have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel-related proteins form 1 family of zinc finger proteins. See ZFP93 (MIM 604749) for additional information on zinc finger proteins.[supplied by OMIM, May 2004],

Function：function:May be involved in transcriptional regulation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 11 C2H2-type zinc fingers.,tissue specificity:Ubiquitously expressed at low levels. Highest levels are found in pancreas and liver.,

Subcellular Location：Nucleus .

Expression：Ubiquitously expressed at low levels. Highest levels are found in pancreas and liver.