Target：TRFM

Gene Name：MFI2 MAP97

Protein Name：Melanotransferrin (Melanoma-associated antigen p97) (CD antigen CD228)

Human Gene Id：4241

Human Swiss Prot No：P08582

Mouse Swiss Prot No：Q9R0R1

Immunogen：Synthesized peptide derived from human protein . at AA range: 210-290

Specificity：TRFM Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：81kD

Background： The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants. [provided by RefSeq, Jul 2008],

Function：function:Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.,similarity:Belongs to the transferrin family.,similarity:Contains 2 transferrin-like domains.,tissue specificity:Found predominantly in human melanomas and in certain fetal tissues; also found in liver, epithelium, umbilical chord, placenta and sweat gland ducts.,

Subcellular Location：[Isoform 1]: Cell membrane; Lipid-anchor, GPI-anchor.

Expression：Found predominantly in human melanomas and in certain fetal tissues; also found in liver, epithelium, umbilical chord, placenta and sweat gland ducts.