Target：ZHX2

Gene Name：ZHX2

Protein Name：Zinc fingers and homeoboxes protein 2

Human Gene Id：22882

Human Swiss Prot No：Q9Y6X8

Mouse Gene Id：387609

Mouse Swiss Prot No：Q8C0C0

Immunogen：The antiserum was produced against synthesized peptide derived from human ZHX2. AA range:751-800

Specificity：ZHX2 Polyclonal Antibody detects endogenous levels of ZHX2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ZHX2;AFR1;KIAA0854;RAF;Zinc fingers and homeoboxes protein 2;Alpha-fetoprotein regulator 1;AFP regulator 1;Regulator of AFP;Zinc finger and homeodomain protein 2

Observed Band(KD)：92kD

Background： The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq, Jul 2008],

Function：function:Acts as a transcriptional repressor.,similarity:Belongs to the ZHX family.,similarity:Contains 2 C2H2-type zinc fingers.,similarity:Contains 4 homeobox DNA-binding domains.,subunit:Forms homodimers. Also forms heterodimers with ZHX1 and ZHX3. Heterodimerization with ZHX1 is not necessary for repressor activity. Interacts with NFYA.,tissue specificity:Ubiquitously expressed.,

Subcellular Location：Nucleus . Colocalizes with EFNB1 intracellular domain in the nucleus. .

Expression：Ubiquitously expressed. Expressed in podocytes.