Target:ZFYVE19
Gene Name:ZFYVE19
Protein Name:Zinc finger FYVE domain-containing protein 19
Human Gene Id:84936
Human Swiss Prot No:Q96K21
Mouse Swiss Prot No:Q9DAZ9
Immunogen:The antiserum was produced against synthesized peptide derived from human ZFYVE19. AA range:311-360
Specificity:ZFYVE19 Polyclonal Antibody detects endogenous levels of ZFYVE19 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:ZFYVE19;MPFYVE;Zinc finger FYVE domain-containing protein 19;MLL partner containing FYVE domain
Observed Band(KD):50kD
Background:disease:A chromosomal aberration involving ZFYVE19 is associated with acute myeloblastic leukemia (AML). Translocation t(11;15)(q23;q14) with MLL/HRX.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FYVE-type zinc finger.,tissue specificity:Detected in brain, heart, skeletal muscle, kidney and liver.,
Function:disease:A chromosomal aberration involving ZFYVE19 is associated with acute myeloblastic leukemia (AML). Translocation t(11;15)(q23;q14) with MLL/HRX.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FYVE-type zinc finger.,tissue specificity:Detected in brain, heart, skeletal muscle, kidney and liver.,
Subcellular Location:Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cleavage furrow . Midbody, Midbody ring . Localizes mainly on centrosomes in interphase and early mitosis. Localizes at the cleavage furrow and midbody ring in late mitosis and cytokinesis. .
Expression:Detected in brain, heart, skeletal muscle, kidney and liver.