Target：TAF I p48

Gene Name：TAF1A

Protein Name：TATA box-binding protein-associated factor RNA polymerase I subunit A

Human Gene Id：9015

Human Swiss Prot No：Q15573

Mouse Swiss Prot No：P97357

Rat Gene Id：360893

Rat Swiss Prot No：Q3B7U2

Immunogen：The antiserum was produced against synthesized peptide derived from human TAF1A. AA range:301-350

Specificity：TAF I p48 Polyclonal Antibody detects endogenous levels of TAF I p48 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：TAF1A;TATA box-binding protein-associated factor RNA polymerase I subunit A;RNA polymerase I-specific TBP-associated factor 48 kDa;TAFI48;TATA box-binding protein-associated factor 1A;TBP-associated factor 1A;Transcription factor SL1;

Observed Band(KD)：53kD

Background： This gene encodes a subunit of the RNA polymerase I complex, Selectivity Factor I (SLI). The encoded protein is a TATA box-binding protein-associated factor that plays a role in the assembly of the RNA polymerase I preinitiation complex. Alternate splicing results in multiple transcript variants encoding multiple isoforms.[provided by RefSeq, Jan 2011],

Function：function:Component of the transcription factor SL1/TIFIB complex involved in the assembly of the PIC (preinitiation complex).,subunit:Component of the transcription factor SL1/TIFIB complex which is composed of TBP and at least TAF1A, TAF1B and TAF1C. In the complex, interacts directly with TBP, TAF1B and TAF1C. Interaction of the SL1/TIFIB subunits with TBP excludes interaction with the transcription factor IID (TFIID) subunits. This mutually exclusive binding directs the formation of promoter and RNA polymerase-selective TBP-TAF complexes.,

Subcellular Location：Nucleus.

Expression： Embryo,Skin,