Target:Relaxin 3
Fields:Neuroactive ligand-receptor interaction;Relaxin signaling pathway
Gene Name:RLN3
Protein Name:Relaxin-3
Human Gene Id:117579
Human Swiss Prot No:Q8WXF3
Mouse Swiss Prot No:Q8CHK2
Immunogen:Synthesized peptide derived from the Internal region of human Relaxin 3.
Specificity:Relaxin 3 Polyclonal Antibody detects endogenous levels of Relaxin 3 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:RLN3;INSL7;RXN3;ZINS4;Relaxin-3;Insulin-like peptide INSL7;Insulin-like peptide 7;Prorelaxin H3
Molecular Weight(Da):15kD
Background:relaxin 3(RLN3) Homo sapiens This gene encodes a member of the relaxin family of insulin-like hormones that is expressed predominantly in the brain and plays a role in physiological processes such as stress, memory and appetite regulation. The encoded protein is a precursor that is proteolytically processed to generate a heterodimeric mature form consisting A and B chains interlinked by disulfide bonds. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015],
Function:function:May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142).,similarity:Belongs to the insulin family.,subunit:Heterodimer of a B chain and an A chain linked by two disulfide bonds.,
Subcellular Location:Secreted.