Target：T3JAM

Gene Name：TRAF3IP3

Protein Name：TRAF3-interacting JNK-activating modulator

Human Gene Id：80342

Human Swiss Prot No：Q9Y228

Mouse Gene Id：215243

Mouse Swiss Prot No：Q8C0G2

Immunogen：The antiserum was produced against synthesized peptide derived from human T3JAM. AA range:251-300

Specificity：T3JAM Polyclonal Antibody detects endogenous levels of T3JAM protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：TRAF3IP3;T3JAM;TRAF3-interacting JNK-activating modulator;TRAF3-interacting protein 3

Observed Band(KD)：64kD

Background： The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multi-protein assembly containing the phosphatase 2A catalytic subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],

Function：function:May function as an adapter molecule that regulates TRAF3-mediated JNK activation.,subunit:Binds to the isoleucine zipper of TRAF3 via its coiled-coil domain.,

Subcellular Location：Cell membrane . Golgi apparatus membrane ; Single-pass type IV membrane protein . Lysosome membrane . Mitochondrion outer membrane . Accumulates on the mitochondria after virus infection. .

Expression： Blood,Lung adenocarcinoma,