Target：IGSF4D

Gene Name：CADM2

Protein Name：Cell adhesion molecule 2

Human Gene Id：253559

Human Swiss Prot No：Q8N3J6

Mouse Gene Id：239857

Mouse Swiss Prot No：Q8BLQ9

Rat Gene Id：360687

Rat Swiss Prot No：Q1WIM2

Immunogen：The antiserum was produced against synthesized peptide derived from human CADM2. AA range:131-180

Specificity：IGSF4D Polyclonal Antibody detects endogenous levels of IGSF4D protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CADM2;IGSF4D;NECL3;Cell adhesion molecule 2;Immunoglobulin superfamily member 4D;IgSF4D;Nectin-like protein 3;NECL-3;Synaptic cell adhesion molecule 2;SynCAM 2

Observed Band(KD)：47kD

Background：cell adhesion molecule 2(CADM2) Homo sapiens This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4.1 binding site near the C-terminus. Proteins belonging to the protein 4.1 family crosslink spectrin and interact with other cytoskeletal proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012],

Function：similarity:Belongs to the nectin family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,

Subcellular Location：Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse . Cell projection, axon . Found in the axoplasm of myelinated axons.

Expression： Amygdala,Brain,Stomach,