Target:IFRD1
Gene Name:IFRD1
Protein Name:Interferon-related developmental regulator 1 (Nerve growth factor-inducible protein PC4)
Human Gene Id:3475
Human Swiss Prot No:O00458
Mouse Swiss Prot No:P19182
Rat Swiss Prot No:P20695
Immunogen:Synthesized peptide derived from human protein . at AA range: 280-360
Specificity:IFRD1 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):49kD
Background: This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010],
Function:function:Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal.,similarity:Belongs to the IFRD family.,subunit:Interacts with PSIP1/LEDGF.,tissue specificity:Expressed in a variety of tissues.,
Subcellular Location:nucleus,cytoplasm,
Expression:Expressed in a variety of tissues.