Target:T2R39
Fields:Taste transduction
Gene Name:TAS2R39
Protein Name:Taste receptor type 2 member 39
Human Gene Id:259285
Human Swiss Prot No:P59534
Mouse Swiss Prot No:Q7TQA5
Immunogen:The antiserum was produced against synthesized peptide derived from human TAS2R39. AA range:218-267
Specificity:T2R39 Polyclonal Antibody detects endogenous levels of T2R39 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:TAS2R39;Taste receptor type 2 member 39;T2R39;Taste receptor type 2 member 57;T2R57
Observed Band(KD):36kD
Background: The protein encoded by this gene is a bitter taste receptor that detects green tea catechins, soy isoflavones, and theaflavins. The encoded protein is gustducin-linked and may activate alpha gustducin. This gene is intronless. [provided by RefSeq, Dec 2015],
Function:function:Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.,miscellaneous:Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.,
Subcellular Location:Membrane; Multi-pass membrane protein.
Expression:Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.