Target：SYT8

Gene Name：SYT8

Protein Name：Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII)

Human Gene Id：90019

Human Swiss Prot No：Q8NBV8

Mouse Swiss Prot No：Q9R0N6

Rat Swiss Prot No：Q925B4

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：SYT8 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：44kD

Background： This gene encodes a member of the synaptotagmin protein family. Synaptotagmins are membrane proteins that are important in neurotransmission and hormone secretion, both of which involve regulated exocytosis. Expression of the encoded protein in human pancreatic islets has been connected to activity of the promoter for the insulin gene, on the same chromosome several hundred kilobases away (PMID: 21336277 and 22928559). This association would link response to gluclose to insulin secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014],

Function：function:Not known. As it is truncated compared to orthologs, its function is not obvious.,sequence caution:The sequence differs from that shown because it is a pre-mRNA.,similarity:Belongs to the synaptotagmin family.,

Subcellular Location：Cell membrane ; Single-pass type III membrane protein . Cytoplasmic vesicle, secretory vesicle, acrosome .

Expression： Lung,Placenta,Testis,