Target:IFN-α1
Fields:Cytokine-cytokine receptor interaction;PI3K-Akt signaling pathway;Necroptosis;Toll-like receptor signaling pathway;NOD-like receptor signaling pathway;RIG-I-like receptor signaling pathway;Cytosolic DNA-sensing pathway;JAK-STAT signaling pathway;Natural killer cell mediated cytotoxicity;Alcoholic liver disease;Tuberculosis;Hepatitis C;Hepatitis B;Measles;Human cytomegalovirus infection;Influenza A;Human papillomavirus infection;Kaposi sarcoma-associated herpesvirus infection;Herpes simplex virus 1 infection;Epstein-Barr virus infection;Human immunodeficiency virus 1 infection;Coronavirus disease - COVID-19;Pathways in cancer;Autoimmune thyroid disease;Lipid and atherosclerosis
Gene Name:IFNA1/IFNA13
Protein Name:Interferon alpha-1/13
Human Gene Id:3439
Human Swiss Prot No:P01562
Mouse Swiss Prot No:P01572
Immunogen:The antiserum was produced against synthesized peptide derived from the C-terminal region of human IFNA1/13. AA range:140-189
Specificity:IFN-α1 Polyclonal Antibody detects endogenous levels of IFN-α1 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:IFNA1;IFNA13;Interferon alpha-1/13;IFN-alpha-1/13;Interferon alpha-D;LeIF D
Observed Band(KD):22kD
Background: The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. [provided by RefSeq, Sep 2011],
Function:function:Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.,miscellaneous:Interferons alpha-1 and alpha-13 have identical protein sequences.,polymorphism:Two forms exist; alpha-1a (shown here) and alpha-1b.,similarity:Belongs to the alpha/beta interferon family.,
Subcellular Location:Secreted.
Expression: Cerebellum,Leukocyte,